Doctor Discussion Guide

Is Zypitamag right for you?

If diet and exercise alone are not enough to get your cholesterol on track, ask your doctor about Zypitamag (pitavastatin) tablets. They will decide if this would be a good option to help lower bad cholesterol (LDL-C) and increase good cholesterol (HDL-C).

It is important to know all of the medicines you take. Keep a list of them to show your doctor and pharmacist when you get new medicine.

Is Zypitamag right for you?

Questions to ask your doctor

1 Are my cholesterol levels under control?

Zypitamag can be used along with diet and exercise to lower bad cholesterol (LDL-C) while increasing good cholesterol (HDL-C). Ask your doctor to have your cholesterol levels checked to determine if Zypitamag is right for you!

2 Will taking a statin interact with any of my current medications?

Zypitamag is processed differently in the body than most statins, reducing the likelihood of interacting with certain other drugs. Talk to your doctor about the medicines you are taking while on a statin.

3 Are there any dietary restrictions associated with statin therapy?

Zyptiamag can be taken with grapefruit juice and can be taken once daily, same time each day, with or without food.1

4 What time of the day should I take my statin?

Zypitamag is taken once daily, at the same time each day, with or without food.1

5 Do the new Blood Cholesterol Guidelines affect your choice of statin for me?

The 2018 ACC/AHA Multisociety Guidelines for Management of Blood Cholesterol were recently published. Ask your doctor if these guidelines have any impact on which statin is right for you!2

6 Is my muscle pain a side effect of the current statin I'm on?

Muscle pain, or myalgia, is a commonly reported side effect of statin therapy. Myalgia rates reported by patients treated with pitavastatin at highest dose was 3.1%. If you are currently experiencing muscle pain associated with your current statin therapy, talk to your doctor to see if switching to Zypitamag may be right for you!1

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1 ZYPITAMAG® [prescribing information]. Ahmedabad, India: Cadila Healthcare Ltd; June 2020

2 Grundy et al. J Am Coll Cardiol. 2019; 73(24): e285-e350

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IMPORTANT SAFETY INFORMATION for ZYPITAMAG® (pitavastatin) tablets

Who should NOT take ZYPITAMAG?

ZYPITAMAG is not right for everyone. Do not take ZYPITAMAG if:

  • You have a known allergy to ZYPITAMAG or any of its ingredients.
  • You have active liver problems, including some abnormal liver test results.
  • You are nursing, pregnant or may become pregnant, as it may harm the baby.
  • You are currently taking cyclosporine or gemfibrozil.

What is the most important information I should know and talk to my doctor about?

  • Call your healthcare provider or get help right away if you experience any symptoms of an allergic reaction, such as rash, itching, or hives.
  • Muscle problems may be an early sign of rare, serious conditions. Tell your doctor right away if you have any unexplained muscle pain, weakness, or tenderness, particularly if accompanied by malaise or fever, or if these muscle signs or symptoms persist after discontinuing ZYPITAMAG.
  • Serious liver problems have been reported rarely in patients taking statins, including pitavastatin. Your doctor should do liver tests before you start, and if you have symptoms of liver problems while you are taking ZYPITAMAG. Tell your healthcare provider right away if you feel more tired than usual, have a loss of appetite, upper belly pain, dark-colored urine, or yellowing of the skin or eyes.
  • Tell your doctor about all your medical conditions and medications you take including nonprescription medicines, vitamins, or herbal supplements.
  • Increases in blood sugar levels have been reported with statins, including pitavastatin.
  • Tell your doctor about your alcohol use.
  • Tell your healthcare provider of a known or suspected pregnancy.

What are the most common side effects of ZYPITAMAG?

The most common side effects of ZYPITAMAG in clinical studies were:

  • Back pain
  • Constipation
  • Diarrhea
  • Muscle pain
  • Pain in the legs or arms

This is not a complete list of side effects. Talk to your healthcare provider for more information.

You are encouraged to report negative side effects of all drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How should I store and take ZYPITAMAG?

  • Store ZYPITAMAG tablets at room temperature, in a dry place, and out of the reach of children.
  • Take ZYPITAMAG orally once daily with or without food at the same time each day.
  • Swallow the tablet whole. Do not split, crush, dissolve, or chew.
  • The maximum recommended dosage is ZYPITAMAG 4 mg once daily.
  • If you take too much ZYPITAMAG or you or someone else takes an overdose, call your doctor and/or local Poison Control Center.

Other important information I should know about ZYPITAMAG.

  • ZYPITAMAG has not been studied to evaluate its effect on reducing heart-related disease or death.
  • ZYPITAMAG is available by prescription only.

For additional information, please see the full Prescribing Information.

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