What is Zypitamag?

Zypitamag is a statin which is prescribed by healthcare providers to help manage cholesterol in the blood. Zypitamag can reduce bad cholesterol by up to 44% and can increase good cholesterol by up to 7%. If you have high cholesterol, Zypitamag may be right for you.

1 It's Different

Your body processes Zypitamag differently than other statins.

Why this matters: Zypitamag has a reduced potential to interact with certain medications and foods you may be taking. This allows you to continue to enjoy your delicious grapefruit juice, unlike some other statins.

2 Side Effect Profile

At Zypitamag's highest dose, only 3.1% of patients experienced muscle pain1.

Why this matters: Muscle pain is one of the more common-side effects from statin therapy. 62% of former statin users indicated that side-effects was the reason they stopped taking their medication2.

If you are experiencing side-effects from current statin, ask your doctor if Zypitamag may be an appropriate alternative for you!

3 Adherence Rates

In clinical studies, less than 4% of patients stopped taking 4 mg pitavastatin due to side effects1.

Why this matters: If you have high cholesterol, its important to take your medications as directed. Did you know that 40-75% of patients discontinue their statin just after one year?3,4,5

4 Versus Other Statins

In clinical studies, pitavastatin was demonstrated to be:

  • as effective as atorvastatin (10 and 20 mg)*
  • as effective as simvastatin (20 and 40 mg)
  • better than pravastatin (10, 20 and 40 mg)*

Learn more about how Zypitamag compares with the other statins.

5 Getting Zypitamag

Accessing Zypitamag has never been easier!

There are two easy ways to save with Zypitamag: Our in pharmacy Dual Savings Card Program, or through our new partner Marley Drug a pharmacy that ships across the entire U.S. With Marley Drug, all patients, including those who are uninsured can access Zypitamag for $1.15 per day. No insurance is needed and Zypitamag will be shipped directly to your home! Plus, eligible patients get the first month FREE!

* Pitavastatin has not been studied against 80 mg dose of pravastatin, 40 mg and 80 mg doses of atorvastatin. Please refer to Important Safety Information and full Prescribing Information.
Conditions apply. Please see our Savings Program and Marley Drug webpages for full eligibility criteria.
1 Zypitamag® [prescribing information]. Ahmedabad, India: Cadila Healthcare Ltd; September 2020
2 Cohen JD et al. J Clin Lipidol. 2012;6(3):208-215
3 Simon LA et al. Med J Aust. 1996;164(4):208-211
4 Avorn J et al. JAMA. 1998;279(18):1458-1462
5 Blackburn DF et al. Can J Cardiol. 2005;21(6):485-488



ZYPITAMAG is a cholesterol-lowering medication called a "statin" that, along with a heart-healthy diet, helps to lower "bad" cholesterol (LDL-C) in adults with elevated cholesterol levels.

Who should NOT take ZYPITAMAG?

ZYPITAMAG is not right for everyone. Do not take ZYPITAMAG if:

  • You have a known allergy to ZYPITAMAG or any of its ingredients.
  • You have active liver problems.
  • You are currently taking cyclosporine or gemfibrozil.

What is the most important information I should know and talk to my doctor about?

  • Call your healthcare provider or get help right away if you experience any symptoms of an allergic reaction, such as rash, itching, or hives.
  • Muscle problems may be an early sign of rare, serious conditions. Tell your doctor right away if you have any unexplained muscle pain, weakness, or tenderness, particularly if accompanied by malaise or fever, or if these muscle signs or symptoms persist after discontinuing ZYPITAMAG.
  • Serious liver problems have been reported rarely in patients taking statins, including pitavastatin. Your doctor should do liver tests before you start, and if you have symptoms of liver problems while you are taking ZYPITAMAG. Tell your healthcare provider right away if you feel more tired than usual, have a loss of appetite, upper belly pain, dark-colored urine, or yellowing of the skin or eyes.
  • Tell your doctor about all your medical conditions and medications you take including nonprescription medicines, vitamins, or herbal supplements.
  • Increases in blood sugar levels have been reported with statins, including pitavastatin.
  • Tell your doctor about your alcohol use.
  • Tell your healthcare provider of a known or suspected pregnancy, or if breastfeeding.

What are the most common side effects of ZYPITAMAG?

The most common side effects of pitavastatin in clinical studies were:

  • Muscle pain
  • Constipation
  • Diarrhea
  • Back pain
  • Pain in arms or legs

This is not a complete list of side effects. Talk to your healthcare provider for more information.

You are encouraged to report negative side effects of all drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How should I store and take ZYPITAMAG?

  • Store ZYPITAMAG tablets at room temperature, in a dry place, protected from light, and keep out of the reach of children.
  • Take ZYPITAMAG orally once daily, with or without food, at the same time each day.
  • Swallow the tablet whole. Do not split, crush, dissolve, or chew.
  • The maximum recommended dosage is ZYPITAMAG 4 mg once daily.
  • If you take too much ZYPITAMAG or you or someone else takes an overdose, call your doctor and/or local Poison Control Center.

Other important information I should know about ZYPITAMAG.

  • ZYPITAMAG is available by prescription only.
  • ZYPITAMAG is not approved for use in patients under 18 years of age.

For additional information, refer to full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

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